Volume Depletion
How frequently does volume depletion occur with empagliflozin in patients with HF?
Rates of volume depletion in the HF Trials
EMPEROR-Reduced:1
10.6%
9.9%
EMPEROR-Preserved:2
11.9%
9.6%
Empagliflozin
Placebo
Note:
- HF, heart failure; UTI, urinary tract infection.
- 1. Packer M et al. N Engl J Med. 2020;383:1413; 2. Boehringer Ingelheim Data on File; 3. Empagliflozin (Jardiance®) PH LPI November 2022.